Some medications cause increased sensitivity. These medications might cause topical sensitivity- localized to the area of application or systemic sensitivity affecting your entire body.
There are two types of reaction:
a) Phototoxicity
Where the medication directly affects proteins in the skin causing increased sensitivity or more severe sunburns. Phototoxicity directly affects the skin.
b) Photoallergy
This affects the skin proteins, making them react to UV light to create an allergen that goes into the bloodstream and causes a systemic allergic reaction; the affects are not localized solely to the skin itself. This can have a longer lasting effect.
The following medications may increase skin sensitivity:
- Antibiotics such as cipro, tetracycline and supra based antibiotics
- Non-steroidal anti-inflamatory drugs (NSAIDs)
- Hormones such as estrogen and progresterone which are commonly used in birth control pills and hormone replacement therapy.
- Oral diabetic medications like sulfonylureas (Glucotrol)
- Blood pressure medications such as Diltiazem (Cardizem)
- Transquillizers (e.g. Thorazine or Serentil)
- Acne medications like tretionin
- Some chemotherapy drugs
- Skin products containing vitamin A of alpha-hydroxy acids (AHA)
- Accutane or retina creams
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